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- “Healthy centenarians”, do they exist? Yes, one was found: among 207 studied Danish centenarians, one was free from chronic disease.
- Endocrine regulation of phosphate (Pi) and calcium metabolism.
- How to test your vitamin B12 status.
- LibreOffice Draw: a free Open Source software that can be used to remove your personal information from your laboratory test results.
- COVID-19: learn to avoid infections.
- The content of alpha-linolenic acid in pumpkin seed oil is very low.
- Reactivation of Epstein–Barr virus in COVID-19. Epidemic-level prevalence of active forms of EBV infections and of other herpes virus infections in some geographic areas.
- Curcumin alone is not senolytic – a study by Beltzig et al., 2021.
- There is a regulatory framework for mRNA- and DNA-based therapeutics and gene therapy-like vaccines. It keeps being ignored by the bureaucrats.
- DNA from virus vector vaccines always integrate into the genome of the infected cell. SARS-CoV-2 mRNA from mRNA vaccines would also be able to integrate human genome.
- SARS-CoV-2 infection, certain drugs used to treat SARS-CoV-2, and, possibly, vaccines against SARS-CoV-2, can cause reactivation of the oncogenic virus KSHV.
- Classification and surgical treatment of chronic lymphoedema in the 1950s – a quality text by Archibald McIndoe.
- Cytokine IL-10 as the “Master Regulator” of immune response to infection.
- Prolonged fasting as a medical intervention to protect hematopoietic stem cells (HSCs) from damage during chemotherapy.
- Pfizer’s BNT162b2 mRNA vaccine: “no correlation was seen between levels of neutralizing antibodies (“NT50s”) and adverse effects (“AEs”)”.
- Human saliva is apparently good at neutralizing viruses WITHOUT any vaccination and virus-specific antibodies. A study by Sheikh-Mohamed et al., 2021.
- Tan et al., 2021 (1): Serum of (two of the eight) patients who survived SARS-CoV-1 infection 17 years ago, and were vaccinated with mRNA vaccine against SARS-CoV-2, inhibited by 100% all variants of SARS-CoV-2 and many bat CoVs.
- “Standing desk” is to avoid. A Summary Statement.
- Maeda and coworkers, 2021: “Both young and older vaccinated individuals with good neutralization response would lose mRNA vaccine protection in 6 to 7 months after the 1st dose.”
- A Test: Predict the levels of thyroid hormones, TSH, T3, fT3, T4, and fT4, in these cyclists: “Young elite cyclists can handle 700 grams of carbs and 4800 kCal of total calories a day without apparent metabolic damage.”
- Causes of constipation, osmotic laxatives and prokinetics, safety of polyethylene glycol/macrogol (PEG). Our comments and notes.
- A review of Johnson & Johnson’s COVID-19 adenovirus vector vaccine.
- Tests of thyroid hormones. A summary statement.
- Essentials of RT PCR and other molecular diagnostic for COVID-19. Infection spread by mass PCR-testing.
- A Test of Physiological Literacy: Can exercise cause hyperinsulinemia?
- COVID-19. A “Certificate of Civil Protection Aptitude During Epidemics”: learn to avoid pathogens.
- A Test of Physiological Literacy: can you explain the mechanism of ketoacidosis in 280 characters?
- Draw a curve that shows desirable blood glucose levels during a day. A Test.
- How much protein and fat a day should an endurance athlete consume to cover his daily glucose expenditure? A Test.
- Protected: “An Advantaged Metabolic State” or a nuisance? Adding blood ketones to the list of markers for self-monitoring.
- Young elite cyclists can handle 700 grams of carbs and 4800 kCal of total calories a day without apparent metabolic damage.
- Protected: IGF-1 and insulin during fasting and on restrictive diets.
- Probiotic use can predispose to overgrowth of methanogenic bacteria.
- Low TSH and osteoporosis.
- High LDL particle number: is it really an indication of insulin resistance and/or of an increased risk of heart disease?
- The New Neander’s Challenge: Who has the highest uric acid?
- “Healthy fat” and serum uric acid.
- Hyperuricemia.
- COVID-19 update: no herd immunity for the “dumb”, masks do NOT work, “virus denial” does not work.
- The New Neander’s workouts: brisk walking.
- A Working Group on low testosterone in overweight and obese men: is it a good idea to suppress LH with testosterone replacement therapy in asymptomatic men?
- Uric acid in athletes in Stephen Phinney’s early studies.
- Protected: Treatment of COVID-19 in Geneva, Switzerland.
- Urinary creatinine.
- R-effective of SARS-CoV-2 is “infinite”: in many households, if one person gets infected, all the other household members will be infected as well.
- Protected: The problem with collagen. Digestive health.
- Postprandial workouts for eating disorders, mood disorders, digestive health, better sleep, fat loss.
- Protected: The New Neander’s Challenge: What geographic areas can keep R-effective below 1?
- Meat and vegetables bouillon or “consommé”.
- The New Neander’s Challenge: Who has the highest SHBG?
- Protected: Periodic reviewing (reading again) of interesting studies is something that we recommend to medical practitioners, researchers, and people who follow our courses in Physiological Literacy.
- Nose warming.
- Protected: SARS-CoV-2 “R-effective” as a measure of population’s IQ.
- A “Freedom of Speech” page for the article “Another load of absurdities from the strange doctor Paul Mason.”
- Typing long texts without ever looking at the computer screen.
- “Non-susceptible” versus “Immune” and Epidemiology as a branch of propaganda.
- Protected: A lot of men on low-carb diets walk with high SHBG. Is this metabolic profile safe?
- Protected: Defining the wild-type carnivore diet: protein and fat intakes, metabolic profiles, etc. A Working Group.
- Does diamine oxidase (DAO) contained in pork kidney remain active after cooking? And do DAO supplements work?
- CAC score can decrease over time in a notable proportion of people.
- Low-carb high-fat diet (LCHF) dangerously resembles the “high-fat diet” that induces disease and chronic inflammation in mice.
- Protected: Raoult’s IHU hospital is not “the best” anymore: mortality is not zero and is in line with countries that don’t necessarily use hydroxychloroquine. The verdict: Over-fixation on HCQ, under-estimation of steroids, incompetent ICU.
- Phinney and Volek since 2011 say: “Above 1 mmol/L (of blood ketones), more than half of the brain’s fuel comes from ketones.” A Test: is this true?
- A serious error in the way Volek et al. designed their 2016 FASTER study.
- “Primitivism” of online health educators: extreme naiveté in interpretation and treatment of subjects.
- Another load of absurdities from the strange doctor Paul Mason.
- A Test: What is wrong in the diagram of the lipoprotein cycle that the health educator Dave Feldman put in his profile on a social network?
- Protected: An introduction to self-monitoring: blood glucose, blood pressure and other essential markers.
- Postprandial triglycerides on low-carb and high-carb diets.
- Thyroid-stimulating hormone (TSH) and physical activity.
- Insights from magnetic resonance imaging of the colon and small intestine.
- Gall bladder contracted by 42% after 10 grams of fat.
- Measurable changes in serum IL-17 (decrease) and IL-10 (increase) in an animal model of arthritis after Lactobacillus sakei administration.
- A Working Group on SHBG.
- Cooking losses of minerals in foods.
- A call for suppliers of complete blood count analyzers for capillary blood.
- Protected: Paul Saladino’s diet of “raw testicles and 120 grams of honey a day”: how to destroy your metabolic profile in one year. Anthropology.
- Protected: Self-monitoring, an introduction for a new consulting client.
- A call for suppliers of blood pressure measuring devices for our clients and community.
- A Test: Do postprandial triglycerides always rise after a high-fat meal?
- Combined hydroxychloroquine and azithromycin show synergistic effect on SARS-CoV-2 in monkey Vero E6 cells in vitro but may not be effective in human alveoli, pneumocytes and other cells.
- The ability of IFN-gamma to inhibit replication of viruses correlated with the cells’ production of nitric oxide (NO).
- The Th1-Th2 paradigm provides a framework for understanding T cell biology and the interplay of innate and adaptive immunity.
- A Test: Are there any athletes in the two groups who are insulin-resistant?
- Eicosanoid biosynthesis from arachidonic acid (20:4n-6).
- The difference between anti-inflammation and pro-resolution.
- COX-2 and the natural signaling pathways in resolution of acute lung injury.
- Classification of fatty acids.
- Simethicone: “it is possible that the liberated GI gas is more readily absorbed through the intestinal mucosa into the blood stream because of the change in surface tension and the reduction of adherent mucus.”
- HCQ+AZ, the pre-therapy workup and the follow-up: electrolytes, electrocardiogram with corrected QT (Bazett’s formula) and more.
- A test: Calculate the in-hospital mortality in the patients that did not receive either hydroxychloroquine or azithromycin in Marseille, France.
- New York: Only 3% of COVID-19 patients on mechanical ventilation made it out of hospitals alive (as of April 4, 2020).
- “Exposure to bile salts constituted a highly aggressive stress for Saccharomyces boulardii, since all the cells died after 1 h of this treatment.
- Capillary Blood Sampling (by Katja Lemburg).
- Comparison of Complete Blood Count between Venous and Capillary Blood.
- A test: estimate sensitivity and specificity of fever as a test for COVID-19 in a group of subjects.
- Identical epidemic curves of COVID-19 in Belarus (zero lockdowns) and the US in Arpil-June 2020.
- Systolic blood pressure below 90mmHg and assessment of COVID-19 severity with “CRB-65” score.
- Terminology: use “specialist” instead of “expert”.
- 42% seroprevalence for SARS-CoV-2 in an Austrian town. A majority of seropositives reported taste and smell disorders.
- “Rethinking the early intubation paradigm.” Analysis: It was never a “paradigm” but hardcore malpractice.
- Azithromycin in UK’s RECOVERY trials.
- Raoult on flu, antibiotics and viral infections in the French Senate in 2012.
- COVID-19 management in Singapore.
- ACE2 expression in organs and systems most frequently affected in COVID-19.
- Fauci, a strange 79 years old character, who has been involved in sabotage for over 30 years, suddenly warns COVID-19 vaccines can be dangerous.
- Hepatitis B vaccine: only 25% of adults aged above 40 developed antibodies. 75% remained unprotected.
- Protected: The current state of Human Civilization: 5 months to start figuring out the obvious during the COVID-19 epidemic.
- A study from China found that hydroxychloroquine was ineffective in the treatment of mild to moderate COVID-19. Despite a high dose and long administration.
- Chaotic treatment of COVID-19 patients in New York State.
- Lymphocytes, neutrophils and IL-6 and the “Effects of Ageing on the Immune System”.
- Treatment of COVID-19 in Marseille, France.
- Protected: Tracking your food and nutrient intakes.
- COVID-19 in Belarus is reaching a plateau.
- The current “standards of care” for the treatment of COVID-19: “stay at home, and when you can’t breathe anymore, come to the hospital to die”.
- China may be telling the truth about the low number of COVID-19 cases: scientists there struggled to recruit patients for their studies.
- Didier Raoult: “We did not test antibiotics against viruses. Now we do and we realize that a lot of antibiotics are effective against viruses.”
- Chinese Clinical Guidance for COVID-19 Diagnosis and Treatment (7th edition), updated March 16, 2020.
- What proportion of SARS-CoV-2 infections are asymptomatic?
- Chronic administration of hydroxychloroquine in systemic lupus erythematosus (SLE): it is not known yet if it is protective against COVID-19 (April 30, 2020).
- Ethnicity does NOT affect the risks in COVID-19. Vitamin D status may not either.
- The “Korean diet”: only 30 grams of fat a day. A “Korea-nivore diet”?
- A rare good move: the World Health Organization criticized “immunity passports” (April 24, 2020).
- Catastrophic COVID-19 mortality rates among the hospitalized males in the New York City area: above 80 years old – 60.6%, 70-79 years old – 35.8%, 60-69 years old – 18.7%, 50-59 years old – 12.2%, 20-49 years old – around 7%.
- Physiological Literacy on mechanical ventilation in COVID-19: “Only a small proportion of patients—largely those in a cardiac arrest situation—“require” mechanical ventilation.”
- Monastyrsky’s probiotic supplement.
- Obesity is NOT associated with severe COVID-19. Age and hypertension are. Studies from Wuhan (452 patients), Marseille (1061 patients) and New York (1150 patients).
- France keeps breaking records in the COVID-19 mortality rate: 17.66% (as of April 20, 2020). Other “leading European countries” are catching up with France.
- T-cell response to respiratory virus infections.
- Early detection of COVID-19: “If you don’t feel the taste of salt (ageusia); if you lose the sense of smell (anosmia).” KB.
- T cell-mediated immune response to respiratory coronaviruses and vaccines against SARS-CoV that induce immunopathology.
- COVID-19 vaccines are unlikely to protect those who are at a higher risk. A 2006 study: Vaccines fail to generate protective immunity in 50% to 90% of older individuals.
- The White House has finally figured out that “Voice of America” spreads foreign propaganda (April 10, 2020).
- Anemia in COVID-19 patients: an innate immune response? “Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia.”
- Which of the statements on COVID-19 therapies are correct? A Test.
- Long walks to heal joints and ligaments. Tools.
- Inactivation of SARS-CoV-1 by alcohol (ethanol).
- Preparedness audit: are you ready to deal with COVID-19?
- Idiotic medical doctors turned COVID-19 into a Plague: in France, COVID-19 mortality rate in hospitalized patients is reaching 23%, and, on average, it is 14.28% (as of April 10, 2020).
- Definitions of Minimal cytotoxic concentration (MCC), Cytotoxic concentration (CC50), Effective concentration (EC50), Inhibitory concentration (IC50), and Selectivity index (SI).
- Aqueous extract from Urtica dioica reduced E. coli biofilm production.
- Novartis stated they have 50,000,000 doses on hand with another 80,000,000 doses to be ready by May.
- On April 8, 2020, France hit a gruesome record as its COVID-19 mortality rate reached 13.35%. Causes: sabotage of bureaucracy and medical incompetence.
- SARS-CoV utilizes angiotensin-converting enzyme 2 (ACE2) to infect host cells. What is ACE2?
- Corticosteroid administration depletes lymphocytes and increases neutrophils in peripheral circulation.
- High doses of corticosteroid methylprednisolone for 1–2 days early in the course of acute respiratory distress syndrome (ARDS) may be harmful.
- There is an antibody-dependent enhancement (ADE) of SARS-CoV-1 infection. Notably, some vaccines enhance infection.
- A 2020 study: young subjects vaccinated with flu vaccine had a 36% higher risk to be infected with a coronavirus.
- There was a systematic use of corticosteroids at early stages of COVID-19 by doctors in China.
- Two other common coronaviruses do not fulfill Koch’s postulates.
- Viruses use peptide expressed on cellular membrane as “receptors” to enter host cells and then downregulate the expression of these peptides. SARS-CoV-1,2 and ACE2.
- All pneumonia cases are now “COVID-19”: people who need hospitalization all end up coinfected with SARS-CoV-2 in hospitals.
- Ian Lipkin, a New York professor of medicine, director of infection and immunity, used a wrong dosage of hydroxychloroquine to treat his COVID-19.
- Neutrophils role as a part of the inflammatory and immune response and COVID-19 associated pathology.
- Hydroxychloroquine has a half-life of 2963 hours (123.5 days). Hydroxychloroquine toxicity, dosage.
- Protected: CAC and Lp(a).
- Orwellian “Doublethink”: A New York doctor would not use hydroxychloroquine to treat COVID-19 because it is against “The Party Line” (March 29, 2020).
- Toxicity of chloroquine and hydroxychloroquine.
- “Acid Related Diseases—Biology and Treatment” by I.M. Modlin, G. Sachs.
- Our notes on the “Corona Virus” SARS-CoV-2 and the disease it causes (COVID-19). (From March 18 to April 9, 2020).
- Protein (casein, 40g) ingested by athletes immediately before sleep is effectively digested and absorbed. KB.
- Oral Candida and microbes as a source of gastrointestinal contamination. KB. Tools.
- How Candida presence in stool correlates with symptoms and complaints.
- Saccharomyces boulardii is NOT resistant to bile acids. Is supplementation with it useless?
- Physiologically literate way to reduce eye bags.
- Olive oil may not be the ideal dietary fat: oleic acid promotes proliferation of cancer cells.
- Feel good about your blood pressure.
- Elemental sulfur is a fungicide used by plants.
- Physiological and pathological outcomes of inflammation.
- Dangers of using coffee enemas.
- Urtica dioica lectin (UDA) is inhibitory to virus cytopathicity. KB.
- Guessing postprandial insulin.
- Logical thinking and the utility of the CAC score.
- Circadian testosterone fluctuation in athletes and in sedentary. A Test.
- Candida fungi, one of the likely culprits of your digestive troubles.
- Both oral glucose and a mixed meal lower testosterone in healthy men.
- Schematic representation of the pathway of the biogenesis of HDL.
- A laborious but wrong diagram of testosterone regulation in obesity.
- High vitamin B12 levels: Is it a reason for concern? A Test.
- Biogenic amines. A 2018 review.
- Transferrin and lactoferrin.
- Effect of dietary fibers on iron absorption.
- Prominent abdominal adiposity in a professor from the University of Calgary, Canada.
- Protected: Milk-derived bioactive peptides undergo complete degradation by probiotic lactic bacteria. Good or bad?
- Despite fasting glucose in the diabetic range, Shawn Baker looks exceptionally well as of January 2020.
- Loss of nitrogen in sweat.
- Deconstructing Stephen Phinney’s early studies.
- Protected: How a physiologically illiterate “expert” is hurting himself.
- Protected: Use text-to-speech to go through longer texts.
- Ingestion of ascorbic acid in daily doses up to 4 g produces only a slight increase in urinary oxalate.
- For athletes: Preventing, slowing the progression and reversing arterial calcification in athletes (CAC score).
- EMAS Sexual Function Questionnaire (EMAS–SFQ).
- Borderline anemia in an enthusiastic carnivore dieter.
- Sources, bioavailability, and metabolism of different forms of vitamin K2: MK9 vs MK4.
- When he is 85, his biological age is 33. The “Optimal Phenotype” explained.
- Changes in plasma myoglobin and creatine kinase levels: before, and up to 72 hours after rugby matches.
- By 74 years of age, a majority of healthy life-long exercises are on statins. This makes their CAC progress faster.
- Objective symptoms of low testosterone on carnivore, ketogenic, low carb, or other restrictive diets.
- How to measure blood pressure.
- Protected: Long-distance running and CAC score.
- Low testosterone in overweight men: why luteinizing hormone does not go up to compensate?
- Tolerable Upper Intake Levels (UL), Vitamins.
- “Fluid Intelligence” of the Brits from the UK Biobank study: test results.
- High probability of osteopenia in another keto/carnivore “success story”.
- Aging-related and innate cognitive impairment: test your “Fluid Intelligence”.
- Consulting Programs: Preventing, slowing the progression and reversing arterial calcification (CAC score).
- Glucose-induced toxicity in GnRH releasing neurons in vitro.
- The power of placebo: Placebo followed by placebo produced the highest, 89%, remission rate in ulcerative colitis.
- Helminth infections: prevention advice.
- Vitamin D content of meat, as a backup for supplements.
- Eskimo used to get their vitamin C together with fish tapeworms.
- Debunking Nina Teicholz: The dietary guidelines tell us to eat low carb (100g/d of carbs). Nina has not read them.
- Does estrogen cause breast cancer? The opinion of Avrum Bluming and Carol Tavris.
- Dr. Brenard Lown: Why there are more than 1 million annual invasive coronary procedures, if there is no mortality benefit compared with medical treatment?
- The perils of postmenopausal hormonal profile.
- Testosterone and sperm production in octagenarian males.
- Dr. Malcolm Kendrick is critical of coronary artery calcium (CAC) score and other “preventive screening”.
- Is your diet a “nutritional fetish”?
- How to redact your laboratory tests before sending them by email with the help of free software. Redact = remove personal information.
- Markers the most associated with liver fat content. And a test.
- Do people at Virta Health understand the physiology of ketosis? Do you? A Test.
- Minnesota starvation experiment.
- Caloric restriction (CR) for weight loss: “10% CR” and “30% CR”, both high carb, produced similar weight loss.
- Protein-energy wasting (PEW).
- Valter Longo’s “FMD” in humans and mice in perspective: mice lose 15% of body weight in 4 days of FMD.
- This may be why you feel lethargic: “spontaneous physical activity” dropped by almost a half after prolonged dietary restriction.
- Debunking Valter Longo: What happens to human organs during caloric restriction or fasting?
- Weight loss and menstrual cycle on a high carb diet: “despite the severe weight loss, none of the four women missed a menstrual period.”
- Protected: Are there natural alternatives to the popular peptides? (A work in progress.)
- Protected: “Who prescribed you metformin?” (A work in progress.)
- Protected: How to minimize the number of laboratory tests if you are in a country with predatory pricing.
- Can we test lactose intolerance at home? Or do we need “genome testing”?