If overweight or obese men have no symptoms of hypogonadism, further alteration of their hormonal profile with a testosterone replacement therapy is a questionable decision.
Tag: LH
Both oral glucose and a mixed meal lower testosterone in healthy men.
Is it possible that elevated fasting blood glucose chronically suppresses testosterone levels by acting at GnRh releasing neurons? This is not excluded. Thus, if we take the same example of Shawn Baker, we can see low levels of testosterone. And while there may be other factors that influence Shawn’s testosterone levels, a causal link between Shawn’s high fasting blood glucose and low testosterone can not be excluded.
Low testosterone in overweight men: why luteinizing hormone does not go up to compensate?
A Test of Physiological Literacy.
Glucose-induced toxicity in GnRH releasing neurons in vitro.
Normally, when testosterone drops, the feedback mechanism should stimulate LH secretion to compensate for the drop in testosterone level. This, however, is not observed systematically after meals.