Tag: Menopause

Twenty-four-hour serum TSH concentration time series in 24 healthy men and 22 healthy women. Blood samples were taken every 10 minutes for 24 hours. Blood sampling started at 9AM. Lights were off between 11PMand 7:30AM. Data are shown as the group mean and SEM. [Reproduced from F. Roelfsema et al: Thyrotropin secretion profiles are not different in men and women.J Clin Endocrinol Metab. 2009.

Low TSH and osteoporosis.

Prolonged fasting diminishes thyroid-stimulating hormone (TSH) secretion by reducing burst amplitude and by blunting the nocturnal increase. It is recognized that TSH plays a role in maintaining bone health. If following a restrictive diet results in the suppression of the nocturnal rise in TSH and diminished burst of the hormone, it may be detrimental to bone health.

Does estrogen cause breast cancer? The opinion of Avrum Bluming and Carol Tavris.

Does estrogen cause breast cancer? The opinion of Avrum Bluming and Carol Tavris.

Avrum Bluming and Carol Tavris argue convincingly against estrogen as a causal factor in breast cancer. It is to note, however, that in our review of the published literature, we did notice a correlation between breast cancer and a phenotype where both estrogen and IGF-1 were elevated at the same time. Additional research in this area is needed. Simply dismissing estrogen involvement in postmenopausal breast cancer and being enthusiastic about hormone replacement are not the conclusions that we draw at our current understanding of the problem.